There are a number of things that you need to remember to do when looking to prevent gyno from happening. Selective estrogen receptor modulators are drugs that work by binding to the estrogen receptors making it difficult for estrogen to bind with other receptors. This will prevent the effects of estrogen related side effects. The most popular drugs are known as Nolvadex and Clomid.
Aromatise inhibitors are also drugs that stop the aromatizing of estrogen. This means that it prevents androgens from converting into estrogens. Running letrozole will suppress your sex drive, which is another reason why it is important to act on preventing gyno as soon as possible.
Letrozole is the most powerful AI to inhibit estrogen using a dose as low as .25mg. You should start running letro about 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. If you do decide to use a letro, there is really no need to use another SERM. There is the misconception that more is better but in reality it is not. Remember, if letro is preventing the conversion of androgens to estrogen, then there is no estrogen. So what would be the purpose of a SERM be when there is no estrogen to bind to the receptors? The way to know if you have developed gyno is if there is a lump behind your nipple, which will be hard and also tender to the touch.
Here is a recommended dosage of letro:
Day 1- .50mg
Day 2- 1mg
Day 3- 1.5mg
Day 4- 2mg
Day 5- 2.5mg
It is very important to remember regardless of the anti-estrogens you are using to still use it for the first day you begin letro because it will not take effect and you by no means want your body to be without any protection when gyno is already happening.
With your estrogen being completely inhibited there is a definite estrogen rebound when your body tries to stabilize the testosterone and estrogen balance. To further prevent this rebound effect, supplement another AI or SERM. When you come to the end of your cycle you will need to use Nolva to make sure you begin taking it on your last day you take your letro.
To reverse the effects of gyno when you have already waited longer than you should have, you should use tribulus or another natural testosterone booster. This isn’t guaranteed but is should help depending on how long you waited. The suggested dosage of Nolvadex when on your off cycle is 20mg starting for a week and then lowering it to 10mg for another week and then come off it completely.