Discussion on Testosterone Replacement Therapy
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 Test, HCG , AI Protocol Question
Been running test (160mg - 80mg x 2), HCG (1,000iu - 500iu x 2) and Anastrozole (.5mg - .25mg x 2) weekly for the last 7 months or so. My question is has anyone else dropped HCG from there protocol for an extended period of time. And if so, any noticable changes other than the expected shrinkage? I'm trying to get dailed in enough that I can get away without an AI or HCG. Although Doc has not stated so, I suspect the HCG is the main culprit in my estro spikes. Also I should mention that I'm married with two kids so no need to maintain sperm count.
Thanks for any info/input.
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I know a lot of guys on this forum have dropped the HCG or have never started taking it. Lets hope some of them report in for you.
For me I have been taking the HCG for two years. My girl loves my huge balls so I dont want them shrinking on her. I dont think you can drop the AI if your still using the HCG tho.
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 Originally Posted by boaterkevin
Been running test (160mg - 80mg x 2), HCG (1,000iu - 500iu x 2) and Anastrozole (.5mg - .25mg x 2) weekly for the last 7 months or so. My question is has anyone else dropped HCG from there protocol for an extended period of time. And if so, any noticable changes other than the expected shrinkage? I'm trying to get dailed in enough that I can get away without an AI or HCG. Although Doc has not stated so, I suspect the HCG is the main culprit in my estro spikes. Also I should mention that I'm married with two kids so no need to maintain sperm count.
Thanks for any info/input.
Hi Kevin, do you have any bloodwork since you have been on this protocol?
HcG is used to stimulate the testes to produce testosterone. it is used to prevent the effects of testicular atrophy, and also to help prevent total loss of testicular function for fertility reasons by stimulating cells that respond to LH and FSH. Stopping HcG can cause fertility issues in the future, but there is anectdotal evidence that people have restarted their own systems after years on T only HRT.
If you were not concerned with any of these, there would be no issue dropping HcG and monitoring bloodwork soley through testosterone injections. You will have to use your bloodwork and the way you feel to gauge your E2 levels as this varies from person to person.
@160mg a week and that dose of HcG i would think that your levels would be in the upper ranges or even off the charts (>1100)
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Maybe slightly off topic, but do you fellas notice that when you use HCG on cycle, apart from maintaining optimal testicular size, are your ejaculate loads much bigger than when you don't use the HCG and your testicles atrophy? This cycle is the first I've used HCG and my loads are phenomenal.
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 Originally Posted by Rastas
Maybe slightly off topic, but do you fellas notice that when you use HCG on cycle, apart from maintaining optimal testicular size, are your ejaculate loads much bigger than when you don't use the HCG and your testicles atrophy? This cycle is the first I've used HCG and my loads are phenomenal.
thats a good question because your balls produce sperm only and sperm accounts for only a small equation of your load. But it could be the whole protocol in itself is producing more hormes which may be stimulating the process. But good question.
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I dropped Hcg qbout 2 months ago, in my 6 months of trt I never felt better. I was hqving estrogen problems with hcg and now I'm off it and inject 80mg of test every 3.5 days and I don't take an ai anymore either. I feel great.
Yea my balls have shrunk, but I've had a vestectomy so no more kids. Living where its humid and hot big nuts suck, I really don't mind at all. As for load size, size is the same only being dialed in I ejaculated harder now than than when I was on Hcg and feeling just so so.
A little off topic but my wife and I watcha little porn. It's crazy how many muscle heads on porn we noticed have shruken nuts, they're definately on test or trt without Hcg and they don't have any issues.
Last edited by cdy2179; 06-20-2012 at 05:41 PM.
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I wonder how little HCG could you get away with using if you didn't want your balls to shrink, could you get away with 100 iu/week? Wonder if that would be the answer or should I say happy medium to none at all. I'd be curious to see the blood work on someone who uses 500-1000iu HCG/e5d then drop down to 100iu/e5d what would your LH and FSH look like? I also have not seen any studies using low doses compared to higher doses. I use 500iu/e5d and my FSH and LH are like .1 or something (basically shut down) not sitting in front of my blood work right now so on 100iu/e5d would they completely shut down?
Just a thought since HCG seems like it screws up dialing in TRT
I really like my nuts kind of attached to them, don’t want them to shrivel away also I still have a few years to decide if I want kids or I should say want a new wife to have kids with.
Last edited by BZOERB; 06-20-2012 at 07:31 PM.
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 Originally Posted by BZOERB
I wonder how little HCG could you get away with using if you didn't want your balls to shrink, could you get away with 100 iu/week? Wonder if that would be the answer or should I say happy medium to none at all. I'd be curious to see the blood work on someone who uses 500-1000iu HCG/e5d then drop down to 100iu/e5d what would your LH and FSH look like? I also have not seen any studies using low doses compared to higher doses. I use 500iu/e5d and my FSH and LH are like .1 or something (basically shut down) not sitting in front of my blood work right now so on 100iu/e5d would they completely shut down?
Just a thought since HCG seems like it screws up dialing in TRT
I really like my nuts kind of attached to them, don’t want them to shrivel away also I still have a few years to decide if I want kids or I should say want a new wife to have kids with.
HcG does not stimulate LH or FSH production (Although HmG does). It mimics them to stimulate leydig cells and sertolli cells in the testes. As for minimum amounts to prevent shrinkage i think this would differ between people. Dr Crisler in some of his reports state that 2x250iu 2 days and 1 day before T injection is enough to keep leydig cells from total shutdown. Although this may not correlate with testicle size.
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 Originally Posted by RedLang
HcG does not stimulate LH or FSH production (Although HmG does). It mimics them to stimulate leydig cells and sertolli cells in the testes. As for minimum amounts to prevent shrinkage i think this would differ between people. Dr Crisler in some of his reports state that 2x250iu 2 days and 1 day before T injection is enough to keep leydig cells from total shutdown. Although this may not correlate with testicle size.
I believe in his paper he did mention testicle shrinkage prevention using the protocol you posted. I believe the paper I read was from 2004.
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Glad to see others have reduced dosage or dropped it all together. I have labs coming up next week and will be curious to see if being off it for the last 4 weeks has any impact. I don't dislike HCG, I just hate constantly chasing my Estro. Nothing worse than drifting in and out of the sweet spot every month or so. One week libido is through the roof and others no AM wood or anything. Gets frustrating. One of the few downsides of TRT so far.
Thanks for the responses.
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If your taking an AI like anastrozole keeping the HCG should not be a problem. Its just the issue of finding the right balance on how much AI you need to take vs how much test and HCG your using.
Keep your dosages consistant over time and try to dial it in. Once your dialed in then just stick with those dosages.
If you dont want to use an AI - then thats a different problem.
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I do not mind using an AI but I do feel that the HCG makes it difficult to stay dialed in for some reason, like someone said, one week you are great the next week you are fighting your E2 kind of a pain in the ass. Not changing anything either just seems to happen for some reason, so if I could get away with test and Ai I would but Im not ready to let my nuts go.
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I'm in the exact same situation as you, I'm thinking about cutting HCG to 250iu a week to see if there's any shrinkage or not. Even after I had split up my shots to 3x a week my estro is still high out of range so my only option is to increase AI and/or cut back on HCG and while I'm not concerned with fertility I don't want to completely shrink. I'm currently doing 500iu hcg a week, I guess it's worth trying to cut in half just to see what happens.

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