Anabolic steroids, bodybuilding discussion forums. - Steroidology

rui products
 

(Forum for members to discuss information on over the counter supplements)
Sponsored by:

Results 1 to 3 of 3
  1. #1
    Community Veteran
    Longtime Vet
    liftsiron's Avatar
    Join Date
    Sep 2003
    Location
    MI
    Posts
    816
    Rep Power
    12
    Prevention of diabetes, hepatic injury, and colon cancer with DHEA
    Prevention of diabetes, hepatic injury, and colon cancer with DHEA
    Their title not mine. This review/research used a combination of animal studies and human interventions to come to this recommendation.

    Posted by jboldman on SBI

    ==============================

    J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):469-72. Related Articles, Links


    Prevention of diabetes, hepatic injury, and colon cancer with dehydroepiandrosterone.

    Aoki K, Nakajima A, Mukasa K, Osawa E, Mori Y, Sekihara H.

    Third Department of Internal Medicine, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan. caa90130@pop06.odn.ne.jp

    The levels of dehydroepiandrosterone (DHEA) and its sulfate (DHEA-S) peak in human in their twenties, then decrease gradually with age. The physiological importance of DHEA was not clear until recent research reports showing that DHEA has beneficial effects on preventing diabetes, malignancy, inflammation, osteoporosis, and collagen disease. We summarize our results concerning diabetes, hepatitis, and colon cancer.In 1982, Coleman et al. [Diabetes 31 (1982) 830] reported that DHEA decreased hyperglycemia in diabetic db/db mice, which become insulin resistant. We measured hepatic gluconeogenic enzymes in an attempt to elucidate the mechanical mechanism of DHEA action. The activity and gene expression of hepatic gluconeogenic enzyme such as glucose-6-phosphatase (G6Pase) was increased in db/db mice despite hyperinsulinemia compared to control db/+m mice. DHEA, like troglitazone, decreased these levels in db/db mice. We also showed that DHEA improved the insulin resistance caused by aging or obesity using the glucose clamp technique in another animal model. In humans, the serum DHEA concentration was shown to be associated with hyperinsulinemia in diabetes. It also became clear that DHEA increased insulin secretion in old-aged db/db mice. DHEA increases not only insulin sensitivity due to the effects in the liver and muscle, but also insulin secretion.As an effect of DHEA on T-cell mediated hepatitis induced by concanavalin A (ConA), DHEA reduced hepatic injury by inhibiting several inflammatory mediators and apoptosis. As an effect of DHEA on carcinogenesis, DHEA would be a potential chemopreventative agent against colon cancer because it decreases the number of azoxymethane (AOM) induced aberrant crypt foci, which is a possible precursor to adenoma and cancer in a murine model.Thus, since DHEA has many beneficial effects experimentally, we should consider administration of DHEA in the future, and common mechanisms among these actions of DHEA should be elucidated in further studies.

  2. #2
    Rookie cifyabimb's Avatar
    Join Date
    Apr 2010
    Location
    Sweden
    Posts
    1
    Rep Power
    0
    Hello everybody
    Hello I am new here.

    I am sorry if this
    is not the right place for this, but I was hoping some one here on [url=http://www.steroidology.com]Steroidology.com[/url] would be able to help me access facebook from work as it it is currently restricted.

    Any help would be greatly appreciated

    Thank you :-)

  3. #3
    Junior Bodybuilder RockG's Avatar
    Join Date
    Feb 2010
    Location
    TX, USA
    Posts
    169
    Rep Power
    5
    Great INFO ON DHEA, I supplement with GNC megamen/DHEA and also my kiropracter has a pharma brand that are dropplets under toungue.. He had been preaching for years and I started supplementing last year.

Thread Information
Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Similar Threads
  1. By GigGuns21 in forum Supplement Forum
    Replies: 16
    Last Post: 10-24-2006, 02:33 AM
Tags for this Thread
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
  

3Js Nutrition Network

juicepump













3Js Nutrition Network

need to build muscle

health and fitness talk