Quote:
Originally Posted by Aztech
R-ala is said to increase insulin sensitivity.
If extrogenous insulin can lead to a gain in fat, please tell me why r-ala could not do this as well?
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glucorell (r-lipoic) modulates the effects of insulin (primarily via ppar-gamma). It actually reduces the lipogenic (fat "making"/storing) effects of insulin.
to clear up your specific misunderstanding, when someone increases insulin sensitivity it means that they need LESS insulin. Since homeostasis is the watchword of most body systems this means that you will produce less insulin as well.
type ii diabetes is when your insulin sensitivity becomes so poor that you cannot produce enough insulin to overcome it (the pancreas's ability and capacity to produce insulin is limited- though that limitation varies-- which is also part of why some extremely obese people dont have diabetes- and other people who only have moderate decreases in insulin sensitivity can have type II- they either dont have a powerhouse pancreas or they have some other glucose disposal issue that exacerbates minimal insulin resistance)