Anabolic steroids, bodybuilding discussion forums. - Steroidology

Share
Easily share your videos with everyone, public or private
Watch
Better than TV! Watch what you want, when you want!
Upload
Quickly upload and tag videos in almost any video format
rui products
 

(Forum for members to discuss the use of anabolic steroids)

Page 1 of 7 12345 ... LastLast
Results 1 to 25 of 156
Like Tree18Likes
  1. #1
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Thumbs up Peptides: Tissue Growth & Protection and Practical use surrounding them *A must read*
    Peptides, Tissue Growth & Protection and Practical use surrounding them

    Hello all of you in internet land!
    Today I wish to cover the subject of peptides and their possible uses.
    There seems to be a lot of people out there unsure of what peptides are or flat out think they are some sort of gimmick.
    I was at one point in time in the same boat, so no worries keep reading and you might learn something. After many years of research on this topic and countless personal experiences with peptides I feel I am qualified to try to help others out there by putting together this article covering the most popular peptides, their uses, how to use them safely and most effectively.

    What so WHAT in the world is a PEPTIDE???

    Isn***8217;t that the stuff in my wife's shampoo???

    Well.... it might be. But not all peptides are the same! Just like not all amino acids are the same.
    Peptides are actually very similar to amino acids (protein molecules) believe it or not.
    A peptide is a short, large molecule of an amino acid molecule that can bind chemically to other molecules to form a larger molecule by peptide bonds. They are listed as a peptide or protein depending on their size.

    I know it sounds confusing and in some ways it is. But it is not too hard to understand them.
    There are many kinds of peptides out there some are your basic protein type peptide that I will not bother to cover at this time or that would make this more of a diet article than a peptide article. Another is a peptide hormone; they are secreted into the blood stream and have an endocrine function in the body.[1]

    There is even something called a neuropeptide. One of many for e.g. is DSIP (Delta Sleep-inducing Peptide). They are small protein-like molecules used by the neurons to communicate.
    They are much smaller than a neurotransmitter and are considered neuronal signaling molecules and they affect many functions in the brain like; pain, hunger, memory and can even effect you're learning abilities!
    Still think Peptides might be a gimmick? HA I sure don't. I think they are GREAT!
    No I won't be talking about neuropeptides today, but I wanted to at least mention them because I feel they are pretty cool and very important.


    Today I will be talking about Peptide Hormones!

    Peptide hormones are not the same as steroid hormones.
    Steroid hormones are synthesized from cholesterol, and are lipids (they are fat based). While peptide hormones are proteins and are formed by a sequence of amino acids.
    As mentioned above these are the ones that have physical effects on the body like growth and repair and has been of very big interest to the bodybuilding scene and in recent years I feel at a massive scale due to the internet and many places selling these peptides.
    I felt I really should put something together about these powerful peptides and how they might help you in your quest to recovery, fat loss and growth.



    I will start with the basics of what each one does then I will get into more detail on how you can use them safely and effectively.

    GHRP-2
    Is a human growth hormone secretagogue. That means it stimulates the body's own release of HGH. It is a ghrelin receptor agonist is also seems to have some protective effect on some tissues and an anti-inflammatory effect as well. The excessive hunger some feel with GHRP-6 use does not seem to be an issue with GHRP-2. The half-life is about 20 minutes so multiple doses per day are optimal.

    GHRP-6
    Is also a human growth hormone secretagogue and stimulates the body's own release of HGH. It is a ghrelin receptor agonist and also seems to have some protective effect on some tissues and an anti-inflammatory effect as well. The half-life is about 20 minutes so multiple doses per day are optimal.
    *Note: GHRP-6 seems to cause excessive hunger in some people compared to GHRP-2. It is not a bad thing per say but depending on if your bulking or cutting you may prefer one over the other.

    CJC-1295
    Is a growth hormone releasing hormone (GHRH) and it aides in the stimulation of the pituitary gland to increase production of growth hormone and stimulates GH and IGF-1 secretion. It will keep a steady increase of HGH without an increase in prolactin as can be an issue for some peptides of this nature. It is an analog to a peptide that is naturally produced to stimulate pituitary production of growth hormone. It has a half-life of about 7-10 days. This means once a week dosing is optimal in most cases.

    CJC-1293
    Is also a growth hormone releasing hormone (GHRH) and it aides in the stimulation of the pituitary gland to increase production of growth hormone and stimulates GH secretion. It is an analog to a peptide that is naturally produced to stimulate pituitary production of growth hormone. The GH pulse from a single administration of CJC-1293 is much greater than that of CJC-1295 but duration is slightly shorter. There is debate on which is better but both are useful regardless in my opinion.

    IGF1 Des
    IGF-1 Des is an IGF-1 analogue of our native igf1 with the last 3 amino acids in the IGF-1 chain removed. That leads it to have little protein binding (good thing), but similar action causing it to be about 10 times more potent than normal IGF-1.[2] The active life is still fairly short, only about 20 minutes making multiple doses daily optimal for some users while others still feel once a day dosing is still worthwhile and the way to go.

    IGF1LR3
    Is also an IGF1 analogue with a 13 amino acid extension at the N-terminus. The alteration leads to less binding in the body greatly extends its half-life from 20min to about 20+ hours. Once a day dosing is optimal.

    IGF1Ec / Mechano Growth Factor (MGF)
    IGF1 Ec is derived from IGF-I but its effects differ from the systemic IGF-I produced by the liver. It is released as a pulse following muscle damage, is involved in the activation of muscle stem cells and also seems to protect the myocardium against ischaemia, which improved cardiac function after heart attacks. There is debate on dosing but i feel post workout (once daily even on non workout days) is a good way to go about it.[3]

    MT2
    Melanotan II (MT2) is a melanocortin. Melanocortins (MCs) are a family of multifunctional peptidergic hormones. MT2 is an analog of these and plays a role in the tanning process but will vary between skin types with its use. It is not really used in any growth as HGH or igf1 would be, but I feel due to its potential skin protection that I should add it in this article even if tanning is not the main focus of this article.



    As you can see all this stuff seems to revolve around IGF1 and HGH, so to understands its effects does not mean needing to fully understand each and every peptide (though a basic knowledge should be known about each one you use). Each peptide is working as either an IGF1 analog or as a HGH releaser and HGH converts to IGH1 giving most of its tissue growing effects anyway.

    It's more understanding what IGF and HGH do in the body, to fully understand what these peptides can potentially do for you.

    I would like to talk mainly about IGF1 as I feel it is the main cause for growth over that of HGH solely.[4]
    The liver is the organ mostly responsible for the production of serum IGF-I even when taking exogenous HGH it is still mainly converted in the liver.

    IGF-1 acts differently in different types of tissues its not all tissues grow from its effects. When active in muscle cells and associated cells they stimulate growth by increasing protein synthesis along with amino acid absorption. IGF-1 also plays a role as a source of energy; IGF mobilizes fat for use as energy in adipose tissue by preventing insulin from transporting glucose across cell membranes. This results in the cells having to switch to burning off fat as a source of energy which I feel is a great quality about IGF-1.IGF also seems to mimic's insulin in the human body. It makes muscles more sensitive to insulin's effects.[5][6]

    I think one of the most interesting effects IGF has on the body is its ability to cause hyperplasia, that is when an actual splitting of cells occurs leading to more cells. You are basically your growing more cells with the use of HGH and IGF-1.
    Hypertrophy is what occurs when practising weight training and steroid use. Hypertrophy is simply an increase in the size of muscle cells but not growing new cells. In humans after you are done puberty you mostly have a set number of muscle cells that you have developed with that doesn***8217;t vary much.All you would be able to do is increase the size of these muscle cells, but you don't actually gain more of them.
    This is not good for someone with bad genetics in the area of muscle cells.
    With IGF use you are able to cause hyperplasia which increases the number of muscle cells and gives you the ability to change your genetic capabilities in terms of muscle tissue and cell count.[6]
    Being able to alter a persons capacity to build muscle density and size is an awesome thing to have control over.
    When you do a cycle of HGH releasing peptides or even straight use of IGF1 analogs on its own, you not only add to growth and recovery while on them, you give yourself a greater number of cells to work with and down the line grow then.

    When you finish a cycle of IGF-1. in a way you are not really finished because you are still left with these new cells regardless of stopping the use of IGF1 or HGH releaser peptides and that is one of the things I just LOVE about HGH and IGF1. The fact you have residual effects is awesome for muscle building!


    OK, OK we know igf1 causes growth of size and cells, but how do I use this stuff effectively?
    Well by knowing the basics of each peptide, how they might have a synergy when used together and fully understanding the effects of HGH and igf1 that's how!

    Unfortunately a lot of the use of IGF1 and HGH by bodybuilders and athletes is an underground trend of their use and you might not find some of the info needed to stack them optimally together or use them in a home setting.
    I wish to give you some of that information here.

    Secretagogues are different from GHRH's, they share no sequence relation and derive their function through action at a different receptor and it has been established that the use of Growth Hormone Releasing Hormone (CJC1295 is one for e.g.) and a Growth Hormone Releasing Peptide (GHRP-6 or GHRP-2 for e.g.) together results in synergistic release of GH from pituitary.
    It is like saying 2+2=5 not 4, if you get what I am trying to say.

    I strongly rec stacking a GHRP with a GHRH for optimal results in tissue growth and fat loss, even if also using an IGF1 analog in the same cycle as some like to do.


    Here are some good examples (in my opinion) of good peptide cycles; (Taken Sub Q is what I rec):


    1#
    Wk1-8 30-60mcg ed IGF-1LR3

    2#
    Wk1-12 1000mcg (1-2mg) every week CJC-1295
    Wk1-12 100mcg 2-4X ed GHRP-2 or GHRP-6
    Wk1-12 10-20mcg ed IGF1 Ec (post workouts) *debatable but some like it*

    3#
    Wk1-12 0.5-1mg 2X a week CJC-1293
    Wk1-12 100mcg 2-4X ed GHRP-2 or GHRP-6

    4#
    Wk1-8 40mcg ed IGF-1LR3
    Wk1-12 0.5-1mg 2X a week CJC-1293
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    5#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des

    6#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des
    Wk1-12 0.5-1mg 2X a week CJC-1293
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    7#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des
    Wk1-12 1000mcg (1mg) every week CJC-1295 (Sub Q)
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    8# (MT2 cycle is for tanning purposes only, dependent on skin type and these are guidelines only)
    Wk1-4 0.5mg 2-3X a week of MT2 (10min tan every week)
    Wk4-8 0.5mg 1X a week of MT2 (10min tan every other week)
    Wk8-? 0.5mg 1X a month of MT2 (tan and dose as needed) *maintenance

    These cycles above would be optimal ways of using these peptides for muscle growth and fat loss. There may be soem argument on what way is best, this is only a guide line.

    Using one or more of the HGH releasing peptides along with an IGF peptide like IGF-1lr3 could lead to growth and more fat loss over just the use of IGF-1lr3.
    But the use of one or more of the HGH releasing peptides without IGF-1 could lead to less total gains in mass as well. So stacking is goal dependent.
    I feel they stack together very nicely personally and I highly recommend IGF1LR3 to my friends new to and interested in peptides.

    IGF1lr3 or IGF1 Des are good peptides to start out with due to the simple ease of their.
    Then once you feel comfortable I would highly recommend stacking it with one of the GHRP's and GHRH's for maximum results.

    There are new discoveries every day in the field of the human body and I would be VERY Happy If I had some effect on this knowledge spreading, so I hope you learned something and enjoyed my article on these peptides and how to use them most effectively and safely.

    I look forward to helping all I can and making more of these kinds of informative articles.
    Till the next time,







    Take care!





    Note: No i did NOT mention all peptides, there are many, I focused on the ones I am interested in and seem to be the most popular. If you have a question about another peptide or something in this post, feel free to PM me and I will try to help if i can.

    Note: I talked to a friend Scientist from a lab that synthesizes (makes) peptides and and he has shown me cjc1293 IS with a long active life but slightly shorter then cjc1295. I have seen some call a simple Mod GRF 1-29 peptide with no dac (fast acting short duration), be called CJC1293 without dac but it does have Dac OR it is not cjc1293 just a Mod GRF with the wrong name.. Just thought I would add this since i have seem a few people call cjc1293 w/o dac when it is not real or would not be CJC1293 (its a LONG story I am trying to keep short and simple, soyry if that doesn't make sense)





    References:
    1) Peptide Hormone Secretion/Peptide Hormone Action: A Practical Approach 2 Volume Set Author: K.Siddle, J. C. Hutton, Oxford University Press, 1991
    2) Des(1***8211;3)IGF-1 Treatment Normalizes Type 1 IGF Receptor and Phospho-Akt (Thr 308) Immunoreactivity in Predegenerative Retina of Diabetic Rats A. Kummer,1 B. E. Pulford,2 D. N. Ishii,2 and G. M. Seigel11University of Rochester School of Medicine and Dentistry, Rochester, New York, USA 2 Colorado State University, Fort Collins, Colorado, USA
    3) Heart Lung Circ. 2008 Feb;17(1):33-9 Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction. Carpenter V, Matthews K, Devlin G, Stuart S, Jensen J, Conaglen J, Jeanplong F, Goldspink P, Yang SY, Goldspink G, Bass J, McMahon C. Source Waikato Clinical School, Private Bag 3200, Hamilton, New Zealand. Mechano-growth factor reduces loss of cardia... [Heart Lung Circ. 2008] - PubMed - NCBI
    4) The somatomedin hypothesis: 2001.Le Roith D, Bondy C, Yakar S, Liu JL, Butler A. Clinical Endocrinology Branch, National Institutes of Health, Bethesda, Maryland 20892-1758, USA. derek@helix.nih.gov The somatomedin hypothesis: 2001. [Endocr Rev. 2001] - PubMed - NCBI
    5) Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1.
    6) LeRoith D, Yakar S.Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. derek.leroith@mssm.edu
    Last edited by juced_porkchop; 02-28-2013 at 11:32 AM.

  2. #2
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Post Peptides: Tissue Growth & Protection and Practical use surrounding them *A MUST READ*
    Peptides, Tissue Growth & Protection and Practical use surrounding them

    Hello all of you in internet land!
    Today I wish to cover the subject of peptides and their possible uses.
    There seems to be a lot of people out there unsure of what peptides are or flat out think they are some sort of gimmick.
    I was at one point in time in the same boat, so no worries keep reading and you might learn something. After many years of research on this topic and countless personal experiences with peptides I feel I am qualified to try to help others out there by putting together this article covering the most popular peptides, their uses, how to use them safely and most effectively.

    What so WHAT in the world is a PEPTIDE???

    Isn***8217;t that the stuff in my wife***8217;s shampoo???

    Well***8230;***8230; I might be. But not all peptides are the same! Just like not all amino acids are the same.
    Peptides are actually very similar to amino acids (protein molecules) believe it or not.
    A peptide is a short, large molecule of an amino acid molecule that can bind chemically to other molecules to form a larger molecule by peptide bonds. They are listed as a peptide or protein depending on their size.

    I know it sounds confusing and in some ways it is. But it is not too hard to understand them.
    There are many kinds of peptides out there some are your basic protein type peptide that I will not bother to cover at this time or that would make this more of a diet article than a peptide article. Another is a ***8220;peptide hormone***8221; they are secreted into the blood stream and have an endocrine function in the body.[1]

    There is even something called a neuropeptide. One of many for e.g. is DSIP (Delta Sleep-inducing Peptide). They are small protein-like molecules used by the neurons to communicate.
    They are much smaller than a neurotransmitter and are considered neuronal signaling molecules and they affect many functions in the brain like; pain, hunger, memory and can even effect you***8217;re learning abilities!
    Still think Peptides might be a gimmick? HA I sure don***8217;t. I think they are GREAT!
    No I won***8217;t be talking about neuropeptides today, but I wanted to at least mention them because I feel they are pretty cool and very important.


    Today I will be talking about Peptide Hormones!

    Peptide hormones are not the same as steroid hormones.
    Steroid hormones are synthesized from cholesterol, and are lipids (they are fat based). While peptide hormones are proteins and are formed by a sequence of amino acids.
    As mentioned above these are the ones that have physical effects on the body like growth and repair and has been of very big interest to the bodybuilding scene and in recent years I feel at a massive scale due to the internet and many places selling these peptides.
    I felt I really should put something together about these powerful peptides and how they might help you in your quest to recovery, fat loss and growth.



    I will start with the basics of what each one does then I will get into more detail on how you can use them safely and effectively.

    GHRP-2
    Is a human growth hormone secretagogue. That means it stimulates the body's own release of HGH. It is a ghrelin receptor agonist is also seems to have some protective effect on some tissues and an anti-inflammatory effect as well. The excessive hunger some feel with GHRP-6 use does not seem to be an issue with GHRP-2. The half-life is about 20 minutes so multiple doses per day are optimal.

    GHRP-6
    Is also a human growth hormone secretagogue and stimulates the body's own release of HGH. It is a ghrelin receptor agonist and also seems to have some protective effect on some tissues and an anti-inflammatory effect as well. The half-life is about 20 minutes so multiple doses per day are optimal.
    *Note: GHRP-6 seems to cause excessive hunger in some people compared to GHRP-2. It is not a bad thing per say but depending on if your bulking or cutting you may prefer one over the other.

    CJC-1295
    Is a growth hormone releasing hormone (GHRH) and it aides in the stimulation of the pituitary gland to increase production of growth hormone and stimulates GH and IGF-1 secretion. It will keep a steady increase of HGH without an increase in prolactin as can be an issue for some peptides of this nature. It is an analog to a peptide that is naturally produced to stimulate pituitary production of growth hormone. It has a half-life of about 7-10 days. This means once a week dosing is optimal in most cases.

    CJC-1293
    Is also a growth hormone releasing hormone (GHRH) and it aides in the stimulation of the pituitary gland to increase production of growth hormone and stimulates GH secretion. It is an analog to a peptide that is naturally produced to stimulate pituitary production of growth hormone. The GH pulse from a single administration of CJC-1293 is much greater than that of CJC-1295 but duration is shorter. There is debate on which is better but both are useful regardless.

    IGF1 Des
    IGF-1 Des is an IGF-1 analogue of our native igf1 with the last 3 amino acids in the IGF-1 chain removed. That leads it to have little protein binding (good thing), but similar action causing it to be about 10 times more potent than normal IGF-1.[2] The active life is still fairly short, only about 20 minutes making multiple doses daily optimal for some users while others still feel once a day dosing is still worthwhile and the way to go.

    IGF1LR3
    Is also an IGF1 analogue with a 13 amino acid extension at the N-terminus. The alteration leads to less binding in the body greatly extends its half-life from 20min to about 20+ hours. Once a day dosing is optimal.

    IGF1Ec / Mechano Growth Factor (MGF)
    IGF1 Ec is derived from IGF-I but its effects differ from the systemic IGF-I produced by the liver. It is released as a pulse following muscle damage, is involved in the activation of muscle stem cells and also seems to protect the myocardium against ischaemia, which improved cardiac function after heart attacks. There is debate on dosing but i feel post workout (once daily even on non workout days) is a good way to go about it.[3]

    MT2
    Melanotan II (MT2) is a melanocortin. Melanocortins (MCs) are a family of multifunctional peptidergic hormones. MT2 is an analog of these and plays a role in the tanning process but will vary between skin types with its use. It is not really used in any growth as HGH or igf1 would be, but I feel due to its potential skin protection that I should add it in this article even if tanning is not the main focus of this article.



    As you can see all this stuff seems to revolve around IGF1 and HGH, so to understands its effects does not mean needing to fully understand each and every peptide (though a basic knowledge should be known about each one you use). Each peptide is working as either an IGF1 analog or as a HGH releaser and HGH converts to IGH1 giving most of its tissue growing effects anyway.

    It***8217;s more understanding what IGF and HGH do in the body, to fully understand what these peptides can potentially do for you.

    I would like to talk mainly about IGF1 as I feel it is the main cause for growth over that of HGH solely.[4]
    The liver is the organ mostly responsible for the production of serum IGF-I even when taking exogenous HGH it is still mainly converted in the liver.

    IGF-1 acts differently in different types of tissues its not all tissues grow from its effects. When active in muscle cells and associated cell***8217;s they stimulate growth by increasing protein synthesis along with amino acid absorption. IGF-1 also plays a role as a source of energy; IGF mobilizes fat for use as energy in adipose tissue by preventing insulin from transporting glucose across cell membranes. This results in the cells having to switch to burning off fat as a source of energy which I feel is a great quality about IGF-1.IGF also seems to mimic's insulin in the human body. It makes muscles more sensitive to insulin's effects.[5][6]

    I think one of the most interesting effect***8217;s IGF has on the body is its ability to cause hyperplasia, that is when an actual splitting of cells occurs leading to more cells. You are basically your growing more cells with the use of HGH and IGF-1.
    Hypertrophy is what occurs when practising weight training and steroid use. Hypertrophy is simply an increase in the size of muscle cells but not growing new cells. In humans after you are done puberty you mostly have a set number of muscle cells that you have developed with that doesn***8217;t vary much.All you would be able to do is increase the size of these muscle cells, but you don't actually gain more of them.
    This is not good for someone with ***8220;bad genetics***8221; in the area of muscle cells.
    With IGF use you are able to cause hyperplasia which increases the number of muscle cells and gives you the ability to change your genetic capabilities in terms of muscle tissue and cell count.[6]
    Being able to alter a person***8217;s capacity to build muscle density and size is an awesome thing to have control over.
    When you do a ***8220;cycle***8221; of HGH releasing peptides or even straight use of IGF1 analogs on its own, you not only add to growth and recovery while on them, you give yourself a greater number of cells to work with and down the line grow then.

    When you finish a cycle of IGF-1***8230;. in a way you are not really finished because you are still left with these new cells regardless of stopping the use of IGF1 or HGH releaser peptides and that is one of the things I just LOVE about HGH and IGF1. The fact you have residual effects is awesome for muscle building!


    OK, OK we know igf1 causes growth of size and cells, but how do I use this stuff effectively?
    Well by knowing the basics of each peptide, how they might have a synergy when used together and fully understanding the effects of HGH and igf1 that***8217;s how!

    Unfortunately a lot of the use of IGF1 and HGH by bodybuilders and athletes is an underground trend of their use and you might not find some of the info needed to stack them optimally together or use them in a home setting.
    I wish to give you some of that information here.

    Secretagogues are different from GHRH's, they share no sequence relation and derive their function through action at a different receptor and it has been established that the use of Growth Hormone Releasing Hormone (CJC1295 is one for e.g.) and a Growth Hormone Releasing Peptide (GHRP-6 or GHRP-2 for e.g.) together results in synergistic release of GH from pituitary.
    It is like saying 2+2=5 not 4, if you get what I am trying to say.

    I strongly rec stacking a GHRP with a GHRH for optimal results in tissue growth and fat loss, even if also using an IGF1 analog in the same cycle as some like to do.


    Here are some good examples of ***8220;peptide cycles***8221; (Taken Sub Q):


    1#
    Wk1-8 40mcg ed IGF-1LR3

    2#
    Wk1-12 1000mcg (1mg) every week CJC-1295
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6
    Wk1-12 10-20mcg ed IGF1 Ec (post workout***8217;s)

    3#
    Wk1-12 100mcg 2-3X ed CJC-1293 (CJC w/o Dac)
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    4#
    Wk1-8 40mcg ed IGF-1LR3
    Wk1-12 100mcg 2-3X ed CJC-1293 (CJC w/o Dac)
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    5#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des

    6#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des
    Wk1-12 100mcg 2-3X ed CJC-1293 (CJC w/o Dac)
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    7#
    Wk1-8 10-20mcg 1-2X ed IGF-1 Des
    Wk1-12 1000mcg (1mg) every week CJC-1295 (Sub Q)
    Wk1-12 100mcg 2-3X ed GHRP-2 or GHRP-6

    8# (MT2 cycle is for tanning purposes only, dependent on skin type and these are guidelines only)
    Wk1-4 0.5mg 2-3X a week of MT2 (10min tan every week)
    Wk4-8 0.5mg 1X a week of MT2 (10min tan every other week)
    Wk8-? 0.5mg 1X a month of MT2 (tan and dose as needed) *maintenance

    These cycles above would be optimal ways of using these peptides for muscle growth and fat loss.

    Using one or more of the HGH releasing peptides along with an IGF peptide like IGF-1lr3 could lead to growth and more fat loss over just the use of IGF-1lr3.
    But the use of one or more of the HGH releasing peptides without IGF-1 could lead to less total gains in mass as well. So stacking is goal dependent.
    I feel they stack together very nicely personally and I highly recommend IGF1LR3 to my friends new to and interested in peptides.

    IGF1lr3 or IGF1 Des are good peptides to start out with due to the simple ease of their.
    Then once you feel comfortable I would highly recommend stacking it with one of the GHRP***8217;s and GHRH***8217;s for maximum results.

    There are new discoveries every day in the field of ***8220;the human body***8221; and I would be VERY Happy If I had some effect on this knowledge spreading, so I hope you learned something and enjoyed my article on these peptides and how to use them most effectively and safely.

    I look forward to helping all I can and making more of these kinds of informative articles.
    Till the next time,







    Take care!









    References:
    1) Peptide Hormone Secretion/Peptide Hormone Action: A Practical Approach 2 Volume Set Author: K.Siddle, J. C. Hutton, Oxford University Press, 1991
    2) Des(1***8211;3)IGF-1 Treatment Normalizes Type 1 IGF Receptor and Phospho-Akt (Thr 308) Immunoreactivity in Predegenerative Retina of Diabetic Rats A. Kummer,1 B. E. Pulford,2 D. N. Ishii,2 and G. M. Seigel11University of Rochester School of Medicine and Dentistry, Rochester, New York, USA 2 Colorado State University, Fort Collins, Colorado, USA
    3) Heart Lung Circ. 2008 Feb;17(1):33-9 Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction. Carpenter V, Matthews K, Devlin G, Stuart S, Jensen J, Conaglen J, Jeanplong F, Goldspink P, Yang SY, Goldspink G, Bass J, McMahon C. Source Waikato Clinical School, Private Bag 3200, Hamilton, New Zealand. Mechano-growth factor reduces loss of cardia... [Heart Lung Circ. 2008] - PubMed - NCBI
    4) The somatomedin hypothesis: 2001.Le Roith D, Bondy C, Yakar S, Liu JL, Butler A. Clinical Endocrinology Branch, National Institutes of Health, Bethesda, Maryland 20892-1758, USA. derek@helix.nih.gov The somatomedin hypothesis: 2001. [Endocr Rev. 2001] - PubMed - NCBI
    5) Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1.
    6) LeRoith D, Yakar S.Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. derek.leroith@mssm.edu
    Last edited by juced_porkchop; 02-04-2013 at 01:55 PM.

  3. #3
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Default
    Just thought I would post this here also since some people only seem to check the AAS section lol

  4. #4
    Junior Bodybuilder RISE's Avatar
    Join Date
    Jan 2009
    Posts
    163
    Rep Power
    6
    Default
    Awesome post! Thanks man.

  5. #5
    Junior Bodybuilder snobE1226's Avatar
    Join Date
    Dec 2011
    Location
    south
    Posts
    190
    Rep Power
    3
    Default
    This is great, have been doing alot of research on peptides lately and this really helps it all come together! Thanks!

  6. #6
    Novice Tugboatz's Avatar
    Join Date
    Jun 2010
    Posts
    67
    Rep Power
    4
    Default
    Wow, awesome post!

  7. #7
    AssHat mlupi319's Avatar
    Join Date
    Aug 2011
    Location
    Buffalo, NY
    Posts
    749
    Rep Power
    3
    Default
    Extremely informative post! I just started reading up on peptides and was lost until I read this.. also I was wondering what do you recommend for a cycle aimed at skin tightening/smoothing? I was thinking about running GHRP-2 and CJC w/o DAC as outlined in cycle #3. Would I see much of an effect with those specific peptides, at those doses, for 12weeks? and how long is it considered safe to run such a cycle?

  8. #8
    j2048b
    Guest
    Default
    i also am interested and have been on other sites asking what a good combo would be! awesome work chop!

    questions: within these cycles of peps, what aas, would couple well with them

    on another note what aas would hamper results as well with these cycles? or not be advised to run while on the peps?

    thanks !!

  9. #9
    Novice Chainman's Avatar
    Join Date
    Jan 2012
    Location
    Smokies
    Posts
    55
    Rep Power
    3
    Default
    Vey interesting, thanks for taking the time to post. Great read!!

  10. #10
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Default
    Quote Originally Posted by j2048b View Post
    i also am interested and have been on other sites asking what a good combo would be! awesome work chop!

    questions: within these cycles of peps, what aas, would couple well with them

    on another note what aas would hamper results as well with these cycles? or not be advised to run while on the peps?

    thanks !!
    Thanks a lot man!
    I was hoping it might help at least one person, seems like it helped a few already which is very nice! :-)

    I don***8217;t think there is a specific AAS that would "hamper" results, though I am sure some are more effective than others is a possibility.

    I think stacking peptides with an aas cycle would be VERY nice.
    When stacking with peptides though I like to rec that people keep it simple, like 1-2 main compounds.

    (In case you are interested) here is a simple aas/peptide cycle that awesome weather cutting or bulking (I rec bulking ;-P)
    wk1-12 400-500mg teste ew
    wk1-12 300-400mg maste ew
    wk1-10 40mcg IGF1LR3 ed

    or some like to use it during post cycle therapy (pct) (may aid in recovery which is a plus!) *I am on Hormone Replacement Therapy (HRT) so not so much my case but something nice to consider*

    wk1-12 500mg teste ew
    wk1-12 300mg maste ew
    wk7-17 40mcg igf1lr3 ed
    wk14-18 post cycle therapy (pct)


    While with some peptides it may take more time to see results like the GHRP or GHRH HGH releasing peptides, you may want to run it throughout the whole cycle and into post cycle therapy (pct) (possibly even passed)

    Kind of like so:
    wk1-14 500mg teste ew
    wk1-14 300mg maste ew
    wk1-18 GHRP-2 100mcg 2-3X ed (total 200-300mcg daily)
    wk1-18 CJC 1293 (w/o Dac) 100mcg 2-3X ed
    wk16-20 post cycle therapy (pct)


    something like the examples above would lead to not only gains in muscle fiber size like normally it would with an aas cycle, but also new cell growth from the peptides, the AAS would also in turn help speed up the growth of the newly formed muscle cells/fibers.

    something like new cell growth then developing them WILL take time, so dont expect to literally see new muscle fiber from one cycle of peptides, but down the line it WILL add up if the rest is done right.


    Hope that helps a bit.

    Take care!
    Last edited by juced_porkchop; 07-06-2012 at 05:51 PM.
    Bigasian and SLIMSHADY99 like this.

  11. #11
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Default
    Quote Originally Posted by mlupi319 View Post
    Extremely informative post! I just started reading up on peptides and was lost until I read this.. also I was wondering what do you recommend for a cycle aimed at skin tightening/smoothing? I was thinking about running GHRP-2 and CJC w/o DAC as outlined in cycle #3. Would I see much of an effect with those specific peptides, at those doses, for 12weeks? and how long is it considered safe to run such a cycle?
    Thanks!

    Sadly I feel with GHRP/CJC cycles (which ARE great) they tend to need a bit more time. I would DEFF bother with 12 weeks of it, but I would strongly rec making 16wks the min if possible.
    Others like 6mo straight.
    Some peptides may raise some other hormones over time like prolactin and cortisol, like ghrp's so even though I would rec an easy 4-6months I would not say year round. Maybe 1 long cycle a year.
    This is just my op though.

  12. #12
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Default
    No prob guys! happy it helped someone.

  13. #13
    Moderator juced_porkchop's Avatar
    Join Date
    Jan 2007
    Posts
    6,797
    Rep Power
    16
    Default
    NO prob guys!
    Happy someone could use it!

  14. #14
    AssHat mlupi319's Avatar
    Join Date
    Aug 2011
    Location
    Buffalo, NY
    Posts
    749
    Rep Power
    3
    Default
    Just read this over in the peptide section, Awesome Info!!

  15. #15
    Junior Bodybuilder mistah187's Avatar
    Join Date
    Oct 2011
    Location
    cali
    Posts
    356
    Rep Power
    3
    Default
    Very Nice post. Been trying g to learn more about peptides the past couple of days so this was good timing.

  16. #16
    GEAR JUNKIE! livebigdieyoung's Avatar
    Join Date
    Oct 2009
    Location
    UK
    Posts
    677
    Rep Power
    5
    Default
    good post! great information!

  17. #17
    j2048b
    Guest
    Default
    awesome man! you have some very informative posts on here and i like to gain as much knowledge as possible, and you help!! so thank you!

    ok so all the cycles i see include mast, what about a basic with var (i know womans gear haha) or even dbol or deca? just wondering what those would best be coupled with? especially if u throw in something like tb-500 for injury reliefe or something along thos lines might be good for post cycle therapy (pct) eh?

  18. #18
    Junior Bodybuilder
    Join Date
    Oct 2011
    Location
    Texas
    Posts
    357
    Rep Power
    0
    Default
    Great post. You did a great job of breaking it down, then stacking up.

  19. #19
    AssHat mlupi319's Avatar
    Join Date
    Aug 2011
    Location
    Buffalo, NY
    Posts
    749
    Rep Power
    3
    Default
    Hey Juced you got any info on fragments? there's what, 2 of them? 177-191 and 176-191...they're supposed to be mainly for fat loss?..how affective are these compared to the peps you've already mentioned?

  20. #20
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Default
    .......,
    Last edited by UserAt204; 07-05-2012 at 10:25 AM.

  21. #21
    Rookie 600@50's Avatar
    Join Date
    May 2012
    Posts
    4
    Rep Power
    0
    Default
    Been looking for this info all in one place for awhile. Thanks man.

  22. #22
    Jacked and Tan MeatHead96's Avatar
    Join Date
    Apr 2011
    Posts
    4,823
    Rep Power
    6
    Default
    good post, thanks pork

  23. #23
    Novice
    Join Date
    May 2012
    Posts
    116
    Rep Power
    2
    Default
    WOW great post Chop!!
    I learned alot!
    I thought I knew more than I did! lol

  24. #24
    Novice
    Join Date
    May 2012
    Posts
    116
    Rep Power
    2
    Default
    now I am NOT jumping into the Tren JUST yet but I have been looking at it and see you mention it here and there.
    would you think this to be a fairly safe and worth while cycle with igf1?

    wk1-10 50mg trenA eod
    wk1-12 500mg teste ew
    wk1-10 30-40mcg IGF1LR3

    Would you do something like this yourself?

    Thanks! :-)

  25. #25
    Novice
    Join Date
    May 2012
    Posts
    116
    Rep Power
    2
    Default
    Great post! thanks

uniquemicals
Page 1 of 7 12345 ... LastLast
Thread Information
Users Browsing this Thread

There are currently 9 users browsing this thread. (0 members and 9 guests)

Similar Threads
  1. Replies: 28
    Last Post: 03-27-2014, 11:32 AM
  2. Replies: 122
    Last Post: 03-20-2014, 05:55 PM
  3. By juced_porkchop in forum Anabolic Steroid Forum
    Replies: 54
    Last Post: 03-11-2014, 02:32 PM
  4. By Symbio in forum Peptide Science
    Replies: 2
    Last Post: 04-26-2013, 02:48 PM
Tags for this Thread
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
  

3Js Nutrition Network

oral anabolics



about steroids



increase my t



health and fitness talk

3Js Nutrition Network

solid muscle isolate 5lb

increase my t