heart and liver protector while using steroids

[brice]

hi everyone .
please i'am starting my test E cycle. i have been doing lots of research on the internet , and people gives ancillaries like HCG and Aromasin , clomid for controlling testes , estrogen while using steroids .

But can anyone give me also some ancillaries to protect the liver and the heart as i read on this website that steroids are also toxic for heart and liver.

thanks for your reply

[Spongy]

Hey Brice, welcome. Give us some more details on your cycle, diet, training history, etc. What are your stats?

To answer your question though, there are many supplements out on the market right now that are specifically designed to act as a liver protectant. Milk Thistle is one ingredient to look for.

This is an old thread, but has some very good info

Liver Protection

[essays]

Hi Brice. Good for you for doing research and caring about your health.

Your primary concern in terms of heart is going to be blood pressure and cholesterol. Supplements like red yeast rice, hawthorn berry, potassium, magnesium and omega 3 fatty acids are going to help BP and Cholesterol. You should be able to google up more solutions if you need.

Liver isn't something you need to worry about with test E. If you were running oral steroids, you would be concerned about your liver.

Be sure you understand what the difference between a SERM and an AI and HCG are, because they all serve different purposes and should be run at different times.

Good luck.

[Spongy]

I completely missed the heart aspect, but what Essay's has said is dead on. The man knows his stuff.

[brice]

Hi Brice. Good for you for doing research and caring about your health.

Your primary concern in terms of heart is going to be blood pressure and cholesterol. Supplements like red yeast rice, hawthorn berry, potassium, magnesium and omega 3 fatty acids are going to help BP and Cholesterol. You should be able to google up more solutions if you need.

Liver isn't something you need to worry about with test E. If you were running oral steroids, you would be concerned about your liver.

Be sure you understand what the difference between a SERM and an AI and HCG are, because they all serve different purposes and should be run at different times.

Good luck.

sorry i didnt mention that my cycle will be made in this way:

Sunday 10mg Aromasin /10mg dianabol
Monday 10mg Aromasin/500iu HCG/10mg dianabol
Tuesday 10mg Aromasin/250mg enanthate/10mg dianabol
Wednesday 10mg Aromasin/10mg dianabol
Thursday 10mg Aromasin/10mg dianabol
Friday 10mg Aromasin/500iu HCG/dianabol
Saturday 10mg Aromasin/250mg enanthate/10mg dianabol

then PCT of clomid , aromasin, hcg , vitamin C and creatine

so just thought about liver protector and heart protector that will suit to this cycle so that i can add it to it

[Spongy]

sorry i didnt mention that my cycle will be made in this way:

Sunday 10mg Aromasin /10mg dianabol
Monday 10mg Aromasin/500iu HCG/10mg dianabol
Tuesday 10mg Aromasin/250mg enanthate/10mg dianabol
Wednesday 10mg Aromasin/10mg dianabol
Thursday 10mg Aromasin/10mg dianabol
Friday 10mg Aromasin/500iu HCG/dianabol
Saturday 10mg Aromasin/250mg enanthate/10mg dianabol

then PCT of clomid , aromasin, hcg , vitamin C and creatine

so just thought about liver protector and heart protector that will suit to this cycle so that i can add it to it

Apparently I did not read this carefully enough. edited...

[essays]

Be sure to run HCG and aromasin for 2 weeks following the last time you inject, THEN start your PCT and stop the HCG.

Spongy bro, I think you glossed over his test E shots, they're tuesday/saturday.

[Spongy]

Be sure to run HCG and aromasin for 2 weeks following the last time you inject, THEN start your PCT and stop the HCG.

Spongy bro, I think you glossed over his test E shots, they're tuesday/saturday.

Christ, I sure did... Post edited.

[brice]

Apparently I did not read this carefully enough. edited...

iam not doing a dianabol only cycle , check properly that i have mentioned test twice a week tuesday and saturday.

[brice]

Be sure to run HCG and aromasin for 2 weeks following the last time you inject, THEN start your PCT and stop the HCG.

Spongy bro, I think you glossed over his test E shots, they're tuesday/saturday.

i have 10 ml test E actually on hand , pls can you tell me it's equal to how much mg ?

following is my PCT , please after my last injection of test E , what shall i continue after the last injection and when to start my PCT:

Day 1-16 : 2500iu HCG every other day. (You may use less HCG if your testes are normal in size AND you have been using HCG on cycle, i.e. 1,000iu HCG etd.)

100/100/100/50 clomid (50mg taken twice per day weeks 1-3 after aas ester clears)

20mg/20mg/20mg/10mg Aromasin (20mg daily for 3 weeks, 10mg daily in week 4)

3g Vit C every day split in 3 doses

10g creatine daily

[brice]

Christ, I sure did... Post edited.

so what do you think about my cycle ? is it ok?

[Phatbastard]

i have 10 ml test E actually on hand , pls can you tell me it's equal to how much mg ?

following is my PCT , please after my last injection of test E , what shall i continue after the last injection and when to start my PCT:

Day 1-16 : 2500iu HCG every other day. (You may use less HCG if your testes are normal in size AND you have been using HCG on cycle, i.e. 1,000iu HCG etd.)

100/100/100/50 clomid (50mg taken twice per day weeks 1-3 after aas ester clears)

20mg/20mg/20mg/10mg Aromasin (20mg daily for 3 weeks, 10mg daily in week 4)

3g Vit C every day split in 3 doses

10g creatine daily

You read the lable and tell us! whats it say 100,200,400?

so what do you think about my cycle ? is it ok?

Ouy NO! but you need to answer the milligrams first

[BBE]

We sell a cycle support designed to be taken while on cycle called n2guard. Protects your liver, controls your bp, etc..

It's a very complete formula. I've had post cycle bloods done on it and was very impressed and pleased.

Read some more about AAS first, and listen to these guys help you plan out a cycle, but should you decide to do it, it is a solid product to keep in mind.

[brice]

We sell a cycle support designed to be taken while on cycle called n2guard. Protects your liver, controls your bp, etc..

It's a very complete formula. I've had post cycle bloods done on it and was very impressed and pleased.

Read some more about AAS first, and listen to these guys help you plan out a cycle, but should you decide to do it, it is a solid product to keep in mind.

where can i get that product from , need to buy that ASAP.

[Spongy]

where can i get that product from , need to buy that ASAP.

needtobuildmuscle.com

It seems like you're kind of jumping into this cycle kind of quickly though. What's your diet and training consist of? You still have yet to give us your stats.

[BigKevKris]

N2 Guard - the one support supplement to rule them all is FINELY here!

Use the code in my signature for 15% off

[Stopstalking]

Need2guard is a great support supplement. I run I along side every cycle.

[tballz]

The best liver protector out there is udca (ursodeoxycholic-acid).

[BBE]

I think udca is a bit overkill in most instances. But yah, no doubt its potent.

[UserAt204]

udca would be better with orals.

10mg dbol a day is pointless. You have 10ml of test so that will only last 5 weeks and you need to run it 10-12 weeks.

Aromisin is typically dosed at 12.5 or 25mg, you adjust this based on need and it's not just for PCT it's to control estro on cycle as well.

Your cycle is way off and a lot of things need to be fixed. There are examples of beginner cycles here. Again don't bother with 10mg of dbol a day and you need to get more test before considering using it.

[weights=life]

^^yeah i was gunna say it didnt look like he had enough for a cycle. Only mentioned one vial

[brice]

N2 Guard - the one support supplement to rule them all is FINELY here!

Use the code in my signature for 15% off

shall i use n2guard along with my ancillaries (clomid, aromasin, HCG) ? or it's designed to be used alone? What's the dosage and duration of use?? thanks

[BBE]

shall i use n2guard along with my ancillaries (clomid, aromasin, HCG) ? or it's designed to be used alone? What's the dosage and duration of use?? thanks

Use the n2guard while you are ON the orals themselves at the dosage on the bottle, I wanna say it's 7 pills per day. If you have enough left over, or are a real stickler you can run the n2guard throughout your PCT as well.

Usually I drop the n2guard going into PCT and switch to something cheaper like liv52.

[BigKevKris]

Dosage is 7 pills per day as directed for 30 days......Well thats how long the bottle lasts

[heavyiron]

ADVANCED CYCLE SUPPORT Rx™ contains 7 key ingredients for complete 'on cycle' protection.

Milk Thistle (Silybum marianum) - One function of the liver is to detoxify and remove toxins, including heavy metals and chemotherapy, from the body. Milk thistle is a liver protective. It is an antioxidant that helps repair damaged liver cells. Studies have shown evidence that silymarin acts almost solely on the liver and kidney. The antioxidant properties in silymarin are believed to be the protective factors. Laboratory studies demonstrate that silymarin functions as a potent antioxidant, stabilizes cellular membranes, stimulates detoxification pathways, stimulates regeneration of liver tissue, inhibits the growth of certain cancer cell lines, exerts direct cytotoxic activity toward certain cancer cell lines.

NAC (N-Acetylcysteine) - NAC can help to prevent damage to the liver being a powerful anti-oxidant and cell detoxification co-factor, NAC works to eliminate your body of free radicals and heavy metals. N-Acetyl-Cysteine is currently the dietary supplement of choice for building up cysteine or conserving the body's store of Glutathione, Cysteine and other Sulfhydryl anti-oxidant resources. This is very crucial for the body's life functions, as NAC helps the body neutralize toxins, heavy metals, such as mercury.

Hawthorne Berry - is highly recognized herb for the heart and cardiovascular system. It has the ability to dilate (enlarge or open) the coronary arteries (the vessels that supply blood to the heart), thus improving blood and oxygen supply to the heart muscle. It also strengthens the hearts pumping ability (muscle), helping the heart to beat more forcefully and efficiently. In addition, hawthorne appears to dilate the highways of other blood vessels around the body, thereby allowing blood to circulate more freely with less strain on the heart. Another benefit of hawthorne berry is that it harbors potent antioxidant properties, which are believed to exert cholesterol lowering effects and reduce the accumulation of fatty plague in the arteries – the hallmark of atherosclerosis.

Saw Palmetto (Serenoa repens) - is used popularly in Europe for symptoms associated with benign prostatic hypertrophy (enlargement of the prostate). Although not considered standard of care in the United States, it is the most popular herbal treatment for this condition. Saw palmetto was listed in the United States Pharmacopeia from 1906 to 1917 and in the National Formulary from 1926 to 1950. Saw palmetto extract is a licensed product in several European countries. Multiple mechanisms of action have been proposed, and saw palmetto appears to possess 5-?-reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Hormonal/estrogenic effects have also been reported, as well as direct inhibitory effects on androgen receptors and anti-inflammatory properties.

Coenzyme Q10 (CoQ10) - boosts energy, enhances the immune system, and acts as an antioxidant. Clinical research suggests that using coenzyme Q10 supplements alone or in combination with other drug therapies and nutritional supplements may help prevent or treat some of the following conditions: Heart disease, High blood pressure and High cholesterol. Researchers believe that the beneficial effect of CoQ10 in the prevention and treatment of heart disease is due to its ability to improve energy production in cells, inhibit blood clot formation, and act as an antioxidant. Several clinical studies involving small numbers of people suggest that CoQ10 may lower blood pressure. Levels of CoQ10 tend to be lower in people with high cholesterol compared to healthy individuals of the same age.

Celery Seed Extract - 3nB is the active compound that is unique to celery. 3nB was discovered as the active component of celery in response to investigations by researchers seeking to explain some of the medicinal effects of celery including the lowering of blood pressure and the relief of arthritis. High blood pressure is usually the result of too much fluid there is in your blood and how flexible or resistant your blood vessels are. Retention of sodium (salt) leads to increase fluid volume in the blood while hardening of the arteries and the hormones released during stress lead to loss of flexibility or constriction of blood flow. In treating high blood pressure, doctors usually prescribed diuretics (water pills) to reduce the fluid volume and vasodilators to relax the arteries to reduce the resistance of blood flow or beta-blockers to turn down the pumping action of the heart. 3nB appears to help lower blood pressure by both acting as a diuretic and vasodilator through impacting the production of prostaglandins as well as acting in a similar manner to drugs known as calcium-channel blockers. 3nB has also been shown to lower blood cholesterol levels and reduce the formation of arterial plaque in experimental studies. This effect may increase the elasticity of the blood vessels and also lead to lower blood pressure readings. 3nB also appears to promote some effects on areas and systems of the brain that control vascular resistance.

Grape Seed Extract - is a natural plant substance that has a concentrated source of oligomeric proanthocyanidins (OPC). These anti-oxidants help protect cells from free radical damage and also promotes healthy circulation. Grape Seed Extract is rich in polyphenols, a compound that's high in antioxidants. Studies have shown OPC to be more powerful antioxidants than vitamin C, E, and beta-carotene. There are countless studies that demonstrates the many health benefits of grape seed extract. It has been extensively researched across the globe. In the research of Dr. Jacques Masquelier et al., the Pasteur & Huntington Institutes and 7 other leading Universities in Europe, Grape Seed Extract has been shown exceptionally effective fighting against free radicals in the body.

Clinicial Studies on CoQ10

Biochemical functions of Coenzyme Q10

Source: Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA. Abstract

Coenzyme Q is well defined as a crucial component of the oxidative phosphorylation process in mitochondria which converts the energy in carbohydrates and fatty acids into ATP to drive cellular machinery and synthesis. New roles for coenzyme Q in other cellular functions are only becoming recognized. The new aspects have developed from the recognition that coenzyme Q can undergo oxidation/reduction reactions in other cell membranes such as lysosomes. Golgi or plasma membranes. In mitochondria and lysosomes, coenzyme Q undergoes reduction/oxidation cycles during which it transfers protons across the membrane to form a proton gradient. The presence of high concentrations of quinol in all membranes provides a basis for antioxidant action either by direct reaction with radicals or by regeneration of tocopherol and ascorbate. Evidence for a function in redox control of cell signaling and gene expression is developing from studies on coenzyme Q stimulation of cell growth, inhibition of apoptosis, control of thiol groups, formation of hydrogen peroxide and control of membrane channels. Deficiency of coenzyme Q has been described based on failure of biosynthesis caused by gene mutation, inhibition of biosynthesis by HMG coA reductase inhibitors (statins) or for unknown reasons in ageing and cancer. Correction of deficiency requires supplementation with higher levels of coenzyme Q than are available in the diet.



Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes.

Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD.

Source: University of Western Australia Department of Medicine and HeartSearch, Royal Perth Hospital, Perth, Western Australia, Australia.

Abstract

OBJECTIVE:

Our objective was to assess effects of dietary supplementation with coenzyme Q10 (CoQ) on blood pressure and glycaemic control in subjects with type 2 diabetes, and to consider oxidative stress as a potential mechanism for any effects.

SUBJECTS AND DESIGN:

Seventy-four subjects with uncomplicated type 2 diabetes and dyslipidaemia were involved in a randomised double blind placebo-controlled 2x2 factorial intervention.

SETTING:

The study was performed at the University of Western Australia, Department of Medicine at Royal Perth Hospital, Australia.

INTERVENTIONS:

Subjects were randomly assigned to receive an oral dose of 100 mg CoQ twice daily (200 mg/day), 200 mg fenofibrate each morning, both or neither for 12 weeks.

MAIN OUTCOME MEASURES:

We report an analysis and discussion of the effects of CoQ on blood pressure, on long-term glycaemic control measured by glycated haemoglobin (HbA(1c)), and on oxidative stress assessed by measurement of plasma F2-isoprostanes.

RESULTS:

Fenofibrate did not alter blood pressure, HbA(1c), or plasma F2-isoprostanes. There was a 3-fold increase in plasma CoQ concentration (3.4+/-0.3 micro mol/l, P<0.001) as a result of CoQ supplementation. The main effect of CoQ was to significantly decrease systolic (-6.1+/-2.6 mmHg, P=0.021) and diastolic (-2.9+/-1.4 mmHg, P=0.048) blood pressure and HbA(1c) (-0.37+/-0.17%, P=0.032). Plasma F2-isoprostane concentrations were not altered by CoQ (0.14+/-0.15 nmol/l, P=0.345).

CONCLUSIONS:

These results show that CoQ supplementation may improve blood pressure and long-term glycaemic control in subjects with type 2 diabetes, but these improvements were not associated with reduced oxidative stress, as assessed by F2-isoprostanes.

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