Anabolic steroids, bodybuilding discussion forums. - Steroidology

 

(Forum for members to discuss the use of anabolic steroids)

Page 1 of 14 1234511 ... LastLast
Results 1 to 25 of 344
Like Tree1Likes
Thread:

Triptorelin

  1. #1
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Triptorelin
    Has anyone looked into triptorelin for post cycle therapy (pct). Its a GnRH agonist. The claim is that one 100mcg dose will completely restore hpta function. Obviously this sounds a little to good to be true. A few guys got some samples from AO and are posting very positive results. There is no bloodwork yet but they are claiming maintained energy/strength and a huge increase in libido. There are a bunch of reports of this being suppressive and causing basically a chemical castration, but it apparently is not the same compound.

    Anyone tried this?? A few research companies are now selling it. Oh and the guys using it have not used a serm with it and are in their third week of post cycle therapy (pct) with all positive results thus far.

    Who knows, but this may be helpful to post cycle.

  2. #2
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Bump

  3. #3
    TWIGS AND SEEDS
    Join Date
    Jan 2011
    Location
    Low and to the left
    Posts
    653
    Rep Power
    4
    Hey user this is interesting, I really have no idea but am curious how it would work.

  4. #4
    I am banned!
    Join Date
    Nov 2009
    Posts
    477
    Rep Power
    0
    What kinds of cycles did these guys run? Did it say?

  5. #5
    I am banned!
    Join Date
    Dec 2010
    Location
    Dead Center
    Posts
    4,678
    Rep Power
    0
    ya...do I sense a personal experience coming up?? If this is true sign me up!

  6. #6
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Give me a minute and I'll copy some of the info.

  7. #7
    I am banned!
    Join Date
    Nov 2009
    Posts
    477
    Rep Power
    0
    I just read that real quick
    Last edited by Dreaded Pirate Roberts; 03-05-2011 at 09:53 PM.

  8. #8
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Anyone here of this before? This came in an email from one of our sponsors. Lookd pretty interesting!

    -------------------------
    We are excited to be able to bring to the market a new research peptide that that stimulates the hypothalamus to secrete GnRH into the hypophysial portal bloodstream which results in the activation of proteins involved in the synthesis and secretion of the gonadotropins LH and FSH.

    In males LH (Luteinizing hormone) stimulates Leydig cell production of testosterone.

    In males FSH (Follicle-stimulating hormone) stimulates the maturation of seminiferous tubules and spermatogenesis.

    We think this is revolutionary. Why?

    In the past the options may have been clomiphene and tamoxifen. There is a significant amount of research today that illuminates the following side-effects of those SERMs: low libido, erectile dysfunction, emotional instability, ocular toxicity and hepatocellular carcinoma- just to name a few.

    The other option may have been HCG. A fine option. But one that requires a very specific daily protocol, and a protocol that if not followed in a disciplined manner, may damage the endocrine system further.

    Besides, GnRH is a naturally occurring neurohormone. The body does not produce clomiphene citrate, tamoxifen or *HCG naturally (*unless you are pregnant).

    The problem with GnRH in the past has been that in order for it to effectively exert its actions upon the pituitary gland, several pulses over several days would need to be stimulated. These required an infusion pump in many cases. Or if too much GnRH was given it would eventually decrease pituitary secretion of gonadotropins.

    After several agonists and analogues of GnRH later- we now have Triptorelin.

    The research peptide Triptorelin is a decapeptide that is modeled after the hypothalamic neurohormone GnRH, that interacts with the gonadotropin-releasing hormone receptor to elicit its biologic response, the release of the pituitary hormones FSH and LH.

    We have found the exact amount of Triptorelin (100mcg) to administer to stimulate the release of LH and FSH and at the same time not overexert its effects on the pituitary gland.

    That is one-singular injection of Triptorelin (100mcg) to completely restore endocrine function! One and done!!!

    The protocol is found in the Triptorelin test that is used clinically to diagnose disease of the endocrine system. Below is the medical abstract that illustrates the success of this peptide in restoring endocrine function:

    Anabolic steroids purchased on the Internet as a cause of prolonged hypogonadotropic hypogonadism

    Objective
    To report a case of hypogonadotropic hypogonadism due to the chronic abuse of anabolic steroids purchased over the Internet.

    Design
    Case report.

    Setting
    Endocrinology unit of the University of Brescia.

    Patient(s)
    A 34-year-old man.

    Intervention(s)
    A single dose (100 ***956;g) of triptorelin (triptorelin test).

    Main Outcome Measure(s)
    Clinical symptoms, androgen normalization, levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone.

    Result(s)
    Within 1 month, the patient's serum testosterone was in the normal range, and he reported a return to normal energy and libido.

    Case report
    A 34-year-old man presented to our department in September 2008 for loss of libido and energy and for mild depression. He was a computer programmer and a nonprofessional bodybuilder with an unremarkable personal medical history. He admitted to having used doping drugs since he was 21 years old. More specifically, he would perform cycles of intramuscular injections of nandrolone (25 mg) and stanazol (25 mg) daily for 8 weeks, followed by mesterolone (50 mg/day) for 15 days. Then he would then take clomiphene citrate (50 mg/day) for 1 week, followed by an injection of human chorionic gonadotropin (2,000 IU) three times in 1 week. He had repeated these cycles from 1995 to 2005. From 2005 to August 2008, to his nandrolone and stanazol cycle he added an intramuscular injection of boldenone (50 mg) daily for 3 weeks. He said he had bought all the drugs on the Internet.

    The patient was 175 cm tall and 80 kg, and he appeared very muscular and toned. His blood pressure and pulse rate were normal. Examination of his heart, lungs, and abdomen were likewise unremarkable. The physical examination showed normal secondary sexual characteristics, but the genital examination revealed bilateral testicular atrophy (volume 2.9 mL and weak consistence). Despite his testicular atrophy, the semen analysis revealed a normal count (79 x106spermatozoa/mlmL) and mild morphology derangements (between 46% and 58%). The blood count and chemistry were normal, but his level of creatine kinase was 454 IU/L (normal range: 20--170 IU/L), alanine aminotransferase 61 IU/L (normal range: 5--50 IU/L), and aspartate aminotransferase 23 IU/L (normal range: 5--50 IU/L).

    In February 2009, the patient continued to report loss of libido and great tiredness. A second physical examination was performed. His levels of alanine transferase and creatine kinase were all within the normal range, but the endocrinologic investigations were still abnormal with the exception of sex hormone-binding globulin level. *The patients testosterone measured 0.3 ng/mL - normal range is between 2.0 ng/mL and 12 ng/ML. Because the situation had persisted for months after ASS withdrawal, we administered a single dose (100 ***956;g) of triptorelin (triptorelin test), which showed a normal response (Fig. 1). Ten days after the triptorelin test, the patient reported a great amelioration of energy, and his serum testosterone was 7.0 ng/mL. One month later, his serum testosterone was within the normal range, and he reported a return to normal libido and energy.

  9. #9
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Action
    Initially causes surge in luteinizing hormone (LH), follicle-stimulating hormone (FSH), and testosterone levels. After several weeks of therapy, LH and FSH secretion decrease, causing sustained testosterone reduction equivalent to pharmacologic castration.

    The above from:
    triptorelin pamoate - definition of triptorelin pamoate in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.




    This is apparently the other type!!!!!! I believe there is the pamoate and an acetate.
    Last edited by UserAt204; 03-06-2011 at 03:01 AM.

  10. #10
    I am banned!
    Join Date
    Nov 2009
    Posts
    477
    Rep Power
    0
    Wow that sounds amazing. Who's selling it cus I'm gonna order it right now.

  11. #11
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    AO is not up and running right now. Iron dragon also but not %100 sure theirs is the agonist. I also haven't found the guys cycle info yet but neither are new to the game. Basically it's said that to little will do nothing and to much is very bad but 100mcg is a great dose. From what I've read one person took 100mcg two weeks after last shot and did not use any post cycle therapy (pct). He stated his energy and strength are good and libido is great. Of course this is not proof of anything but it's not coming from a noob. There will be bloodwork from them in a week or two. I'm still sceptical but interested.

    It will be worth it to wait for some to post bloodwork. Looks promising but we all know how this stuff can go. I personally like many other peptides and think they work great so I can't wait to see how this turns out. I'm probably going to purchase some and try it myself, but I won't be coming off for a while.

    Also if anyone hasnt heard of HMG that is worth checking out. It's along the lines of hcg but also stimulates fsh. It's expensive though, but I've seen it starting to come down in price and not recommending triptorelin to anyone just looking for some thoughts on it or personal experiences.
    Last edited by UserAt204; 03-06-2011 at 03:02 AM.

  12. #12
    I am banned!
    Join Date
    Nov 2009
    Posts
    477
    Rep Power
    0
    Yea def got me interested. If it does what it says it does that be fantastic. Probably be like 200 bucks for the one shot! Haha keep us updated User.

  13. #13
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    60

  14. #14
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Yeah I will try to find more info. What concerns me is I have not found anything long term because there is the possibilty it could raise numbers for say a month then have them all drop but I'm not sure.

  15. #15
    Pro Bodybuilder BigBlackguy's Avatar
    Join Date
    Jan 2011
    Posts
    1,206
    Rep Power
    4
    Eric over at Primordial is actually working on an article for this... should be up in a few weeks. I'm thinking of trying this. It's key that the testes not atrophy during the cycle (ie, use HCG) that way the LH and FSH kick-start from the triptorelin will work immediately.

  16. #16
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    Nice. Keep us updated

  17. #17
    I am banned!
    Join Date
    Dec 2010
    Location
    Dead Center
    Posts
    4,678
    Rep Power
    0
    Wow...this could be amazing! Fukin got me all worked up now....like always

  18. #18
    TWIGS AND SEEDS
    Join Date
    Jan 2011
    Location
    Low and to the left
    Posts
    653
    Rep Power
    4
    Quote Originally Posted by Cobra Strike View Post
    Wow...this could be amazing! Fukin got me all worked up now....like always
    oh shit, i'm sensing some sausage talk coming up. cobras got himself all worked up

  19. #19
    I am banned!
    Join Date
    Dec 2010
    Location
    Dead Center
    Posts
    4,678
    Rep Power
    0
    Quote Originally Posted by nate212 View Post
    oh shit, i'm sensing some sausage talk coming up. cobras got himself all worked up
    I wake up worked up lol goin to the 20year olds later after I finish up a drug profile on dexamethasone...shes hammered and just text me that she wants me to fuck her ass and use her dildo on her snatch at the same time...I text her back and said I would think about it...

    sorry wasnt the sausage talk you were hoping for...maybe tomorrow lol

  20. #20
    Pro Bodybuilder BigBlackguy's Avatar
    Join Date
    Jan 2011
    Posts
    1,206
    Rep Power
    4
    Quote Originally Posted by Cobra Strike View Post
    I wake up worked up lol goin to the 20year olds later after I finish up a drug profile on dexamethasone...shes hammered and just text me that she wants me to fuck her ass and use her dildo on her snatch at the same time...I text her back and said I would think about it...

    sorry wasnt the sausage talk you were hoping for...maybe tomorrow lol
    LOL

    btw, triptorelin has been known about for a while. It just hasn't been researched for bodybuilding usage. It's also fairly expensive.

  21. #21
    Pro Bodybuilder BigBlackguy's Avatar
    Join Date
    Jan 2011
    Posts
    1,206
    Rep Power
    4
    Dexamethasone - Wikipedia, the free encyclopedia

    Can this be used for performance enhancement before a competition?? Sorry to go offtopic lol

  22. #22
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    The prices I have seen are high for one dose but if it's effective it would be worth the small investment

  23. #23
    Spartan epoxy's Avatar
    Join Date
    Apr 2007
    Posts
    960
    Rep Power
    8
    I think it is a shot in the right direction. From what I read it will restart endocrine function, but you only take 1 dose right? I have heard it can shut right back down. Maybe it is best used in conjunction with a full PCT protocol? Theres a lot of info out there on it, just need to look.

  24. #24
    Pro Bodybuilder BigBlackguy's Avatar
    Join Date
    Jan 2011
    Posts
    1,206
    Rep Power
    4
    Quote Originally Posted by epoxy View Post
    I think it is a shot in the right direction. From what I read it will restart endocrine function, but you only take 1 dose right? I have heard it can shut right back down. Maybe it is best used in conjunction with a full PCT protocol? Theres a lot of info out there on it, just need to look.
    Oh dude, full PCT for sure! I think the idea behind it is that it will start up LH and FSH immediately, as opposed to waiting 2 weeks for the SERM to do its magic.

    I've seen bloodwork where LH is high but testosterone remains low... the testes just weren't responding to it and this usually happens in PCT for people who dont use HCG or something to keep the testes ready to use LH.

  25. #25
    Senior Member
    Join Date
    Dec 2010
    Posts
    6,267
    Rep Power
    0
    A lot of the info is conflicting and I think there are two types. One works then brings you back down very quick. The guys I have been following are three weeks past the one inject and still feeling good but it will take blood to see whats really happening.

uniquemicals
Page 1 of 14 1234511 ... LastLast
Thread Information
Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Tags for this Thread
Posting Permissions
  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
  

3Js Nutrition Network

juicepump







solid muscle isolate 5lb





3Js Nutrition Network



health and fitness talk





solid muscle isolate 5lb